e-ISSN 1694-2078
p-ISSN 1694-2086

Arch Med Biomed Res. 2018;4(1):12-20. doi:10.4314/ambr.v4i1.2

David AN1, Jinadu MY2,1, Gbajabiamila TA1, Herbertson EC1, Wapmuk AE1, Odubela OO1, Musa ZA3

Author Affiliations

1Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria
2Public Health Department, Federal Medical Centre, Ebute-Metta, Lagos, Nigeria
3Monitoring and Evaluation Unit, Nigerian Institute of Medical Research, Yaba, Lagos, Nigeria

correspondence to
Herbertson EC; ebiereh@yahoo.com

Received: August 28, 2017
Accepted: March 07, 2018


Malaria and HIV are causes of severe morbidity and mortality in Sub-Saharan Africa. Individuals with HIV/AIDS are at increased risk of clinical malaria and severe illness. Sub-Saharan Africa has a high HIV prevalence. Anemia as a complication of malaria has been associated with increased mortality in HIV-infected children. This study determined the prevalence of malaria in asymptomatic HIV positive children, and the association between malaria and hematologic parameters in the study population. It is a cross sectional study conducted at the Out Patients’ Clinic, Nigerian Institute of Medical Research, Lagos. Study population comprised HIV infected children aged 1 year - 14 years. 151 children participated in the study between June and November 2016 after a detailed informed consent process. Malaria parasite density, hemoglobin and CD4 cell counts were determined. The prevalence of malaria parasitaemia among participants was 14.6%. Majority had a CD4 count > 500 cells/μL (85.1%). The prevalence of anemia (Hb < 11.0g/dL) was 29.1% in the study population. No statistically significant association was found between CD4 count and hemoglobin concentration with malaria parasitaemia. This study revealed a low prevalence of malaria and anemia amongst asymptomatic HIV positive children.

KEY WORDS: Malaria, Anaemia, CD4, Children, HIV, Prevalence, Lagos


CrossRef Link


This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 3.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.